Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation
نویسندگان
چکیده
منابع مشابه
Reciprocal Repression between Sox3 and Snail Transcription Factors Defines Embryonic Territories at Gastrulation
In developing amniote embryos, the first epithelial-to-mesenchymal transition (EMT) occurs at gastrulation, when a subset of epiblast cells moves to the primitive streak and undergoes EMT to internalize and generate the mesoderm and the endoderm. We show that in the chick embryo this decision to internalize is mediated by reciprocal transcriptional repression of Snail2 and Sox3 factors. We also...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2011
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2011.07.005